1)   MultiMon 2.00
MultiMon is an advanced multifunctional system monitoring tool for Windows which displays highly detailed output of a very wide range of activities in real-time. It is an indispensable tool for system administrators,developers and support engineers.
sysmon, system monitor, registry monitor, regmon, file monitor, filemon, file system monitor, filesys, thread monitor, process monitor,

 2)   Adragon Firewall 7
deny copying/opening/modifying/finding/deleting any specified file;log any access to system files/registry keys;can work without running the main program;
deny copy, no run, access control, file monitor, registry monitor, file safe, system security, system log, no open, no modify,